10.3.2 Consequences of Blood Clotting Related Problem


  1. Haemophilia is a group of hereditary genetic disorders that impair the body’s ability to control blood clotting or coagulation.
  2. As a result, minor injuries and internal bleeding can results in death owing to excessive loss of blood.


  1. Thrombosis is the formation of a blood clot (thrombus) inside a blood vessel, obstructing the flow of blood through the circulatory system.
  2. When a blood vessel is injured, the body uses platelets and fibrin to form a blood clot to prevent blood loss.
  3. However, when a blood vessel is not injured, blood clots may form in the body under certain conditions such as a defective blood vessel causes the blood clotting factors to be released into the blood.
  4. When a blood clot can cause obstruction to the blood flow.
  5. If clotting occurs in the coronary artery, it is called coronary thrombosis. Coronary thrombosis can cause a heart attack.
  6. If it occurs in the artery in the brain, it will cause a stroke.
  7. Thrombosis may also cause atherosclerosis, which is the deposition of fat and cholesterol on the walls of arteries.

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